Sign up to The Recap, our weekly email of editors’ picks. A few short months ago Katarina Johnson-Thompson made a startling confession: despite being one of the best athletes on the planet she suffered from impostor syndrome. Now even she must know that she is the real deal.It was staggering enough to see her go toe-to-toe – and then topple – an all-time great in Nafi Thiam to claim a heptathlon gold medal in Doha. But it was the way she did it that really seared into both skin and soul. Over the two days of competition Johnson-Thompson never gave off a slightest whiff of weakness as she set four individual personal bests to keep Thiam at bay. And then, when victory was in the bag, she continued to push her body through the pain barrier on the final event, the 800m, to score 6,981 points – a tally that surpassed Jessica Ennis‑Hill’s British record of 6,955, which had stood as tall and imposing as an obelisk since London 2012.As Johnson-Thompson burst into tears after crossing the line she said all the injuries, heartbreaks and self-eviscerations during the last few years were worth it. “It makes it more special and sweet for sure,” she said beaming. “This is crazy for me.”Of course, this being Johnson-Thompson it was natural to fear some calamity or other would arise in the 800m, even when she had a 137‑point lead. A trip or a fall, perhaps, or even a random act of God. After all, at the Commonwealth Games last year she injured her calf with just 300m to go and had to do an impromptu triple jump – hop, skipping and jumping her way to victory. But this time there were no travails or torments, just another personal best of 2:07:26 and elation. Katarina Johnson-Thompson threw a personal best in the javelin. Photograph: Kai Pfaffenbach/Reuters Since you’re here… Katerina Johnson-Thompson gives everything down the home straight in the 800m. Photograph: Lucy Nicholson/Reuters Twitter Pinterest … we have a small favour to ask. More people are reading and supporting The Guardian’s independent, investigative journalism than ever before. And unlike many new organisations, we have chosen an approach that allows us to keep our journalism accessible to all, regardless of where they live or what they can afford. But we need your ongoing support to keep working as we do.The Guardian will engage with the most critical issues of our time – from the escalating climate catastrophe to widespread inequality to the influence of big tech on our lives. At a time when factual information is a necessity, we believe that each of us, around the world, deserves access to accurate reporting with integrity at its heart.Our editorial independence means we set our own agenda and voice our own opinions. Guardian journalism is free from commercial and political bias and not influenced by billionaire owners or shareholders. This means we can give a voice to those less heard, explore where others turn away, and rigorously challenge those in power.We need your support to keep delivering quality journalism, to maintain our openness and to protect our precious independence. Every reader contribution, big or small, is so valuable. Support The Guardian from as little as $1 – and it only takes a minute. Thank you. Share on WhatsApp The question was whether Thiam could respond in the javelin. A heavily-strapped arm to protect an injured elbow suggested otherwise, and the Belgian could only throw out to 48.04m – more than 10 metres below her best. Johnson-Thompson’s response? Another personal best of 43.93m.It meant Thiam had to finish nine seconds ahead of her in the 800m – and given that the Belgian’s personal best was eight seconds slower it was never going to happen. “I was always worried,” Johnson-Thompson joked afterwards. “I thought I was going to run out of the line in the 800m and I was going to get disqualified. I didn’t take anything for granted until I saw my name on the scoreboard. Dina Asher-Smith sets sights on being all-time great after Doha 200m triumph “Nafi is a phenomenal athlete, she has set the standard, she is one of the greats like Carolina Klüft. I witnessed 7,000 points first through her. She has raised the bar. I am glad I have been able to step up and be competitive.”No wonder she was elated. It is a long time since she burst into the public’s consciousness at London 2012, an eager young apprentice learning at the feet of Ennis-Hill. Most expected a smooth succession, the flame passing from one Briton to another, but instead Johnson-Thompson had to suffer a seven-year itch before getting her due rewards.Earlier in her career she would constantly visualise herself standing on the podium, the national anthem striking up and a gold medal round her neck, thinking that if she only believed enough it would happen. Athletics Incredibly, she had beaten Thiam, who won silver, by 304 points – the biggest margin of victory in the heptathlon at the world championships since 1987 – with Austria’s Verena Preiner claiming bronze.Johnson-Thompson had laid the groundwork on the opening day, setting personal bests in the 100m hurdles and shot put to lead Thiam by 96 points overnight. If the Briton was nervous going into the second day she disguised it like a master. She started with a massive long jump of 6.77m – her best in a heptathlon and well ahead of the Belgian’s 6.40m – to extend her lead to 216 points and never looked back. Share on LinkedIn Topics Share on Twitter Share via Email Read more If only. There were European and world indoor gold medals, and a Commonwealth Games triumph but when it really mattered injuries and ill-fortune got in the way. At the 2015 world championships she fouled three times in a row in the long jump while favourite. At the 2016 Rio Olympics a quadriceps injury flared up. Then, in front of her home crowd at the London 2017 world championships, she fluffed her lines in the high jump.It did not help either that she was up against Thiam. But she accepted the challenge, and pushed herself to be even better.“The low moments have helped me come back, to make the move to France, to take care of myself,” she said. “I am so happy with this.”She also grew up. For years Johnson-Thompson was a self‑confessed “mummy’s girl” who had most things done for her. But moving to Montpellier in early 2017 to join a renowned group that included Kevin Mayer, the world decathlon record holder, changed everything.“Moving to France has paid off,” Johnson-Thompson said. “It has been such a long road, I am glad I am coming into my best in these next two years.”When she first arrived, her coaches would call her “droopy” because she used to drop her head in competitions, while her trainer, Bertrand Valcin, kept telling her to smile more. On a glorious night in Doha, she fulfilled those orders to the letter. Support The Guardian Read more World Athletics Championships Katarina Johnson-Thompson Share on Messenger news Share on Facebook Pinterest Facebook Facebook World Athletics Championships: Johnson-Thompson wins heptathlon gold – as it happened Twitter Share on Pinterest Reuse this content
Watford captain Deeney urging supporters to get behind themby Paul Vegasa month agoSend to a friendShare the loveWatford captain Troy Deeney is urging supporters to get behind the players.Deeney says the players remained confident that they could still have a good season, but said fans needed to be a bit more patient after the change of head coach from Javi Gracia and Quique Sanchez Flores.”We can’t panic yet. If we start panicking what does that transmit?” said the skipper.”Obviously there’s quality there [in the team], but the main quality that’s needed now is hard work and resilience and not to fold because as you saw tonight at half time, some fans were a bit iffy and it’s six games in. There has to be a sense of realism.”We’re not spending £50 million on centre halves, we’re not paying people 200 grand a week. We’re still Watford, we’re still learning, we’re still building, but when we win, we win together and when we lose, we lose together and that’s where I think we’re getting a little bit lost in the connection between fans and players.”Don’t get me wrong, lose 8-0, you deserve to get battered, we all do. We take that on the chin, but at the same time when we win, be with us.”We’re growing and ultimately changing manager, you’ve got to find your best team and best formation and we’ve got a lot of attacking talent now, so how you mould that and get everyone playing and clicking at the same time. It’s difficult.” About the authorPaul VegasShare the loveHave your say
Quinn Pitcock Dallas Lauderdale Last week: 3-1 Overall: 12-5 Picks: Ohio State, Michigan State, Florida James Laurinaitis Last week: 3-1 Overall: 12-5 Picks: Ohio State, Michigan State, Florida Last week: 3-1 Overall: 9-8 Picks: Ohio State, Michigan State, Florida Zack Meisel Last week: 3-1 Overall: 12-5 Picks: Ohio State, Michigan, Florida Little changed standings-wise last week, as all five participants in the Weekly Picks Challenge correctly predicted three out of the four games. This week, the only game featuring different predictions is Michigan State-Michigan. Justin Zwick remains atop the leaderboard with a 14-3 overall record. A three-way tie for second place has James Laurinaitis, Dallas Lauderdale and defending champion Quinn Pitcock at 12-5. THIS WEEK’S GAMES Indiana @ No. 2 Ohio State No. 17 Michigan State @ No. 18 Michigan No. 14 LSU @ No. 12 Florida Last week: 3-1 Overall: 12-5 Picks: Ohio State, Michigan, Florida Justin Zwick
Categories: Marino News State Rep. Steve Marino today introduced a plan extending a disabled veterans property tax exemption to include un-remarried, surviving spouses of Michigan veterans who died from service-connected causes while on active duty.In 2013, the Disabled Veterans Exemption was created to give property tax exemptions for 100-percent disabled veterans who were honorably discharged from the Armed Forces or their surviving spouse if they have not remarried. Consequently, service members killed while on active duty or from service-connected injuries were unintentionally barred from this benefit due to an oversight in law.“There’s an unfortunate loophole in state law excluding the ability for spouses of those who were killed while on active duty to claim the property tax exemption because their spouse was not technically a veteran at the time of death,” said Marino, of Harrison Township. “My plan is a solution to this inadvertent barrier, and it will ultimately remove a burden facing many Michigan military families.”Marino’s measure, House Bill 4053, now moves to the House Local Government and Municipal Finance Committee for further consideration. 16Jan Marino bill to allow spouses of deceased military heroes property tax exemptions
June 22, 2017 2 min read This story originally appeared on PCMag Snapchat Next Article The new Snap Map has a ‘ghost mode’ that lets you browse a map of your friends’ locations without sharing your own. Fireside Chat | July 25: Three Surprising Ways to Build Your Brand –shares Snapchat Now Lets You Spy on Friends’ Locations Bored Snapchat users looking for something to do should update their apps today: they’ll be greeted with a new map view that shows where exactly their friends are and what they’re up to.Snap Map, as the company is calling it, can be activated by pinching your fingers together on the camera view when you first start the app. Once in map view, you’ll see “Actionmoji” versions of your nearby friends, which include their names and profile photos in a configuration that vaguely resembles the tags you might find on plants for sale at the nursery.When you tap on one of your friends’ icons, you’ll see stories they’ve posted recently, which might get you in the mood to go join in the fun they’re having. You’ll only see your friends on the map if they’ve recently opened their Snapchat map and have shared their location with you. Conversely, you can decide who can see your location on their maps, choosing from all your friends or a customized list. You can also browse the map in “Ghost Mode” without broadcasting your location to anyone.What if none of your friends are around or they haven’t posted anything interesting recently? Not to worry: the map view will also show a heat map based on the activity of other Snapchat users. For example, a map of San Francisco shows hot spots at Fisherman’s wharf and along Market Street. You can also zoom out to view events that Snapchat selects from around the country or the world, such a baseball game or current events like Tuesday’s special election in Georgia.The Snap Map is Snapchat’s take on the location-based social media genre, which already includes startups like Zenly that are designed to let you keep track of nearby friends. And given Instagram’s propensity to successfully duplicate Snapchat features, it also wouldn’t be surprising if Instagram copies the map idea in the near future. Tom Brant Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Add to Queue News reporter Enroll Now for $5 Image credit: Snapchat via PC Mag
Subscribe Now Ricky Williams Has The Last Laugh Once the poster child of a stoner athlete, the ex-NFL running back is is making great strides with his cannabis company. Easy Search. Quality Finds. Your partner and digital portal for the cannabis community. Former NFL running back Ricky Williams remembers when his use of marijuana made him an outcast among both his peers and potential business associates.Williams said that people didn’t want to associate with him because of his use of cannabis. “My past kept haunting me,” Williams told the Roll Up Podcast.That’s all changed for the Pro Bowl running back. Now, he’s become an entrepreneur in cannabis with his line of products called Real Wellness by Ricky Williams. According to his website, he is offering “an herbal approach to everyday wellness.”That may sound like the tagline of any number of marijuana brands. But Williams can claim he was far out in front — and in a very public way — on the issue of marijuana and the potential health benefits.Related: 5 Surprising Truths About Canadian Legalization“Most Infamous Stoner Athlete”In a way, Williams’ experience with marijuana personifies the changing attitudes on cannabis. A decade ago, while a star in the NFL, he became the target of both jokes and the NFL’s substance abuse policy for talking openly about using marijuana.That was an unusual stance from such a big star. And at the time, he was one of the biggest. Between 1999 and 2011, playing mostly with the New Orleans Saints and Miami Dolphins, Williams rushed for more than 10,000 yards, including five 1,000-yard seasons.He also was public about his use of marijuana, becoming “America’s most infamous stoner athlete,” according to Sports Illustrated. He failed four drug tests, all for cannabis use, he told the magazine. In 2004, he decided to retire early and spent the year studying holistic medicine at the California College of Ayurveda.He returned to the Dolphins in 2005. However, in 2006, he missed an entire season for violating the NFL’s substance abuse policy.He told Sports Illustrated that those years in the middle of his career cost him about $5 million to $10 million in salary and endorsements. He’s hoping to make that back, and then some.Related: New California Law Makes it Easier to Erase Old Marijuana ConvictionsEarly AdooterWilliams launched Real Wellness earlier this year in California (a native of San Diego, he now lives in Venice Beach). Both medical and recreational marijuana is now legal in the Golden State. But long before marijuana was the “in” thing, Williams believed in the medicinal value of marijuana. Since leaving the NFL, he ‘s spent his time studying the potential of marijuana for pain management and other conditions.Williams told the Fort Lauderdale Sun-Sentinel: “I am known as a professional football player. In the last 14 years, I have been educating myself and training as a healthcare practitioner.”His products include salves, tonics and vape cartridges, which he says are a “modern reintroduction to the healing power of ancient herbs.” The products contain either CBD or THC, or sometimes both.Williams believes there is a huge and growing market for his product. He saw a microcosm of that market in the NFL. Williams said more than half of the players he played within the NFL used marijuana, including quarterbacks and coaches, according to Sports Illustrated.Follow dispensaries.com on Instagram to stay up to date on the latest cannabis news. Next Article Guest Writer Opinions expressed by Entrepreneur contributors are their own. October 25, 2018 3 min read –shares Add to Queue dispensaries.com Get 1 Year of Green Entrepreneur for $19.99 Green Entrepreneur provides how-to guides, ideas and expert insights for entrepreneurs looking to start and grow a cannabis business. Image credit: My Mystic Journey LA via Twitter Ganjapreneur
Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Elon Musk is hoping to end the U.S. lawsuit over his “pedo guy” statements against British cave diver Vernon Unsworth before it gets started. His attorneys have filed a motion to dismiss the case on the grounds that his insults weren’t serious and thus were protected free speech in the U.S. This was just a “schoolyard spat,” Musk’s attorneys said. They contended that Twitter was a place where you could “expect to read opinions, not facts,” and thus that no one could realistically assume Musk was telling the truth.Unsworth’s attorney rejected the claims in a statement to The Guardian. The argument would “effectively doom all lawsuits” over defamation, and that Musk’s dismissal points were “novel but inaccurate.”Related: What’s Happening on The Entrepreneur Index Right NowIt’s not clear how the judge will respond to the dismissal request, although it might not work in Musk’s favor. While he did apologize for his initial “pedo guy” remark in July, he undercut that in August when he told BuzzFeed News reporter that Unsworth was a “child rapist.” For that matter, Musk ran into trouble with the SEC precisely because he used Twitter to make a serious claim about taking Tesla private. Don’t be surprised if the case moves forward to its initial hearing on April 1st. The Tesla executive says it was just a ‘schoolyard spat.’ Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Next Article Jon Fingas Elon Musk Add to Queue December 28, 2018 This story originally appeared on Engadget Image credit: Robyn Beck | Pool via Engadget Elon Musk Asks Judge to Toss ‘Pedo Guy’ Defamation Lawsuit Enroll Now for $5 –shares 2 min read
Free Webinar | July 31: Secrets to Running a Successful Family Business Add to Queue Internet pioneer Marc Andreessen said that Mt. Gox “had to die,” and it officially just did.After a rocky few weeks practically sputtering on life support, the troubled Bitcoin trading exchange, once most robust in the world, filed for bankruptcy protection in Tokyo District Court today.CEO Mark Karpeles blamed hackers for his company’s demise, saying they exploited a “weakness” in Mt. Gox’s computer system that enabled them to pilfer almost half a billion U.S. dollars worth of the digital currency. Karpeles, like Andreessen and scores of fellow Bitcoin defenders, says he still expects the controversial unregulated virtual currency to grow and thrive, even as his exchange pulls the plug on itself. Related: Bitcoin Exchange Mt. Gox Apologizes About Crippling Hack, Says Withdrawals to Resume Soon”First of all, I’m very sorry,” he said. “The bitcoin industry is healthy and it is growing. It will continue, and reducing the impact is the most important point.”Mt. Gox, which claimed for a time that it oversaw approximately 80 percent of all dollar-for-Bitcoin trades across the globe, said it discovered on Feb. 24 that 750,000 of its customers’ bitcoins were missing, along with 100,000 of its own. That adds up to about $480 million total, approximately 7 percent of the estimated total of bitcoins in existence.The company halted customer withdrawals on Feb. 7 and later wiped out the contents of its website and Twitter feed, sparking accusations of insolvency and rocking the Bitcoin trading community worldwide.Related: Bitcoin Advocate Andreessen: ‘Mt. Gox Had to Die’The widely expected bankruptcy filing comes only one day after Japan’s highest government spokesperson announced that Japanese authorities, along with the country’s Ministry of Finance, are actively investigating angry investor claims that Mt. Gox lost their Bitcoin. Federal prosecutors in New York subpoenaed the trading platform this earlier this month.Meanwhile, as of 9:56 a.m. ET, Bitcoin prices hit $561.24, according to the CoinDesk Bitcoin Price Index. The price dipped below $500 last Monday, its weakest price since November, when it rallied at about $1,200. 2 min read Bitcoin Kim Lachance Shandrow Former West Coast Editor Register Now » February 28, 2014 Next Article Mt. Gox Files for Bankruptcy, Faults Hackers and Flawed System for Collapse Learn how to successfully navigate family business dynamics and build businesses that excel. –shares
Marketing Magic: Monopoly Maker Hides Real Money in Game’s Special Edition Apply Now » Next Article Hasbro is taking a page out of the Willy Wonka marketing playbook. In honor of Monopoly’s 80th anniversary, French players of the eminent board game will have a chance to win actual cash hidden in sets of the game.Eighty boxes out of 30,000 different games will have varying amounts of cash ranging between about $170 and $342. Meanwhile, the big winner will get a box that has every piece of Monopoly money replaced will real euros, adding up to about $23,200.Related: This ‘Exploding Kittens’ Card Game Is Blowing Up on KickstarterWhile certainly not enough to buy a railroad or an ocean-front property, it’s still a fairly substantial chunk of change. Florence Gaillaird, Hasbro France’s brand manager, told the AFP that the bills were delivered to the local packing center with a supreme amount of secrecy.Of course, Monopoly isn’t the first brand to take a “golden ticket” approach. In 2010, Nestle, which owns the Wonka name, put prizes in its Exceptionals candy bars. Two years later, in a slightly more off-putting move, the candy company put GPS trackers in Kit Kats to award 12,000 euros to winners in Ireland and the UK. Monopoly is available in 114 countries and 43 languages. Related: ‘Game Guru’ of Candy Crush Saga Leaves King Digital to Found New Gaming Startup Nina Zipkin 2019 Entrepreneur 360 List February 3, 2015 –shares Entrepreneur Staff Marketing Add to Queue Staff Writer. Covers leadership, media, technology and culture. 2 min read The only list that measures privately-held company performance across multiple dimensions—not just revenue.
Persistent Systems, a leading developer of software products and solutions across a variety of markets including Industrial and Manufacturing, announced it has joined Siemens’ MindSphere Partner Program to deliver its Industrial IoT solutions to market. MindSphere is the cloud-based, open IoT operating system from Siemens that connects products, plants, systems, and machines, enabling businesses to harness the wealth of data generated by the Internet of Things (IoT) with advanced analytics.Persistent is delivering MindSphere solutions for Smart Energy Management, Overall Equipment Effectiveness (OEE) and other related offerings to manufacturing clients in APAC and North America. In addition to offering clients a fast track to remote connectivity and management for machines and programmable logic controller (PLC) assets through its MindSphere “Connect & Monitor” integration services, Persistent offers custom analytics that leverage MindSphere Analytics and Machine Learning service APIs.Marketing Technology News: DirectLync Shakes Up Small Business Marketing with New Digital Marketing PlatformSanjeev Srivastav, General Manager – Industrial & IoT Practice, Persistent Systems“Aside from the benefit of working with a partner like Siemens with a huge installed base of industrial automation controllers, MindSphere can help reduce the amount of time it takes for us to develop applications for our clients, while retaining the option to develop related services on the cloud services from AWS and Microsoft Azure, where Mindsphere is available.”Marketing Technology News: Video Conferencing Equipment Supplier, IVCi, Lists and Explains How Small Businesses Can Benefit from Video ConferencingFlorian Beil, Head of Sales for MindSphere at Siemens PLM Software“Persistent Systems has deep domain expertise in IoT, Analytics and AI/ML and is well situated to deliver MindSphere solutions to firms with complex industrial operations in Discrete and Process Manufacturing sectors. We look forward to collaborating with Persistent Systems to help our joint customers achieve their goals.”Marketing Technology News: Video Conferencing Equipment Supplier, IVCi, Lists and Explains How Small Businesses Can Benefit from Video Conferencing Persistent Systems Joins Siemens’ MindSphere Partner Program to Bring Industrial IoT Solutions to Market PRNewswireMay 6, 2019, 8:02 pmMay 6, 2019 Industrial and ManufacturingInternet of ThingsMarketing Technology NewsMindSphereNewsPersistent SystemsSanjeev Srivastav Previous ArticleMadison Logic Unveils New Data Cloud to Accelerate ABM for B2B Organizations GloballyNext ArticleAmazon or Alibaba: Freedonia Compares These Global E-Commerce Leaders
Opposing Views On Health Law’s Birthday; Krauthammer Calls For Compromise With Obama On Entitlements, Taxes USA Today: Happy Birthday ObamaCare! A year ago, the Affordable Care Act’s outlook appeared uncertain, with the Supreme Court decision on the law’s legality and a contentious election fight over its merits still on the horizon. Today, with both of those events unfolding in favor of the landmark law, ObamaCare continues to take effect, having already achieved so much, yet with so much more to come later this year (Rep. Sander Levin, D-Mich., and Rep. Jim McDermott, D-Wash., 3/21). USA Today: Affordable Care Act Hasn’t Earned Its Name It was three years ago this weekend that President Obama signed a law that fundamentally changed our nation’s healthcare system. While reform was needed, change is only good if it brings with it real reforms that reduce costs and empower individuals and small-business owners in making healthcare choices for themselves, their employees and their families. The Patient Protection and Affordable Care Act (ACA) does neither of those things. Three years later, the law is not living up to its moniker (Dan Danner, Bruce Josten and Mattew Shay, 3/21). The Washington Post: The 50 Percent Solution The proposition that entitlement curbs are the key to maintaining national solvency is widely accepted, though not by many congressional Democrats. President Obama, however, has endorsed it on various occasions. And he could make it happen. If he wants. I remain skeptical that he does. But national solvency is important enough to test this proposition at least once more (Charles Krauthammer, 3/21). Kansas City Star: Medicaid Expansion Is Still A Big Pill For Missouri GOPMissouri’s Republican legislative leaders used their last few hours before spring break to make it known they are not on board with raising the state’s miserly income qualifications for Medicaid. “We do not believe it’s prudent to double down on a broken system,” said Tom Dempsey, the Republican Senate president pro tem. Medicaid actually works very efficiently for a lot of people, but that’s their story and they’re sticking with it. This doesn’t necessarily mean Republicans won’t ultimately expand Medicaid eligibility. Virtually every business group in the state wants them to do so, and Democrats are already sharpening their knives for the campaign season two years hence (Barbara Shelly, 3/21). The New York Times Opinionator: Burgers, Fries And Lies So, Mike Ruffer (a Five Guys franchise owner) was brought in as the star witness at a Heritage forum designed to show just how egregious it is that businesses will have to provide health care for their employees, or pay a fine. Right wing media — Drudge, Breitbart, Fox — played their part, sounding alarms over a cheeseburger that may cost an additional quarter. But what the Heritage histrionics unintentionally showed was everything that is absurd, wrong and darkly humorous about the American approach to diet and health care economics (Timothy Egan, 3/21).The New York Times: North Carolina Overreaches Under the federal Medicaid statute, states must seek reimbursement for medical expenses if the beneficiary also receives money from an insurance company or another third party. This week, the Supreme Court correctly slapped down a North Carolina law that could squeeze far more from beneficiaries than they actually owe (3/21).Minneapolis Star Tribune: North Dakota Governor Should Veto Abortion Limits After losing badly at the polls in Mississippi and Colorado, proponents of life-begins-at-conception measures kept shopping for new states that might not only pass a sweeping abortion ban but also conscript taxpayer dollars to fund proponents’ grander ambition — a legal challenge to Roe vs. Wade. Unfortunately, they found an easy mark with money in oil-rich and socially conservative North Dakota (3/21).Baltimore Sun: Sickening Cuts To NIHAlbert Einstein was 26 when he published his Special Theory of Relativity; James Watson, at age 25, explained the structure of DNA. Here in Baltimore, many great medical achievements were developed by early-career researchers at Johns Hopkins. “The young do not know enough to be prudent,” said Pearl Buck. “They attempt the impossible, and achieve it, generation after generation.” Today’s young American scientists are no less inspired but are discouraged by a perceived lack of opportunity after long, grueling years of training. Unfortunately, the federal budget sequester is turning that perception to reality. We appreciate the nation’s long-term fiscal challenges and recognize that overall spending must be cut. Precisely because of these pressures, not in spite of them, we should reallocate priorities to invest in America’s future (Michael Milken and Elias Zerhouni, 3/21). WBUR: CommonHealth: The Big Lesson From Brill’s ‘Bitter Pill’ Story, So Big It’s Hard To SeeI stopped in to get my car fixed yesterday and found the recent Time issue featuring Steve Brill’s mega-story — Bitter Pill: Why Medical Bills Are Killing Us — still lingering on the waiting-room table, well-thumbed and dog-eared. For a story about a problem that just about everyone already knew existed, the piece has clearly been having a major impact and sparked widespread discussion. Today, the Cambridge-based Institute for Healthcare Improvement posts a lively and provocative piece that concludes that the current payment system is broken and must be blown up (Carey Goldberg, 3/22). Journal of the American Medical Association: Pushing the Outpatient Quality EnvelopeThe rapidly changing payment and delivery system may introduce the risk of many unintended consequences if quality measurement is too myopic. Fortunately, the present era is characterized by more knowledge about quality and more tools to measure quality. Nevertheless, pushing quality measurement for the outpatient setting needs to be a priority for the medical community, and more work must be done to develop, test, and use new measures (Dr. Tara F. Bishop, 3/21). This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
Reviewed by Alina Shrourou, B.Sc. (Editor)May 16 2019″Fly heading two three zero, runway two seven left, cleared for takeoff.” Air traffic controllers are among the 25 to 45 percent of the workforce in the United States who use their voices professionally. It is imperative for their listeners to understand what they are communicating. Air traffic controllers, teachers and university professors have a high prevalence of voice disorders referred to as “dysphonia.” Other professions also are at risk including clergy, attorneys, counselors and performers.Voice disorders are not just a problem for these professions. In fact, 1 in 13 American adults reported a voice problem in the past year. Only a minority of them got treatment, further perpetuating the overall problem. Voice disorders are a common occurrence for many people throughout their lifetime. Although it is well understood how voice disorders impact the speaker, there is little research on how voice disorders impact the listener.Researchers from Florida Atlantic University and Towson University conducted a study to determine if there are differences in speech intelligibility (ability of a listener to recover a speaker’s message) in healthy voices compared to those who have voice disorders such as breathiness, hoarseness, loss of voice or a “croaky” voice. They also wanted to know if using listener “strategies” such as paying close attention to the words or using other words to try to figure out the message would increase speech intelligibility. To date, no studies have investigated if listener strategies improve intelligibility scores in speakers with voice disorders.In addition, the researchers wanted to explore if the listener’s overall impression of a person’s speech or voice quality would impact how they rate speech intelligibility. Speakers with voice disorders are judged more negatively than speakers without voice disorders. The researchers constructed the study to include information to help identify which voice qualities may be at play during a reduction of intelligible speech. A speaker’s intelligibility is impacted not only by the abilities of the speaker, but also by the listening environment and skills employed by the listener. Moreover, listeners receive less salient information to process when they are listening to a person with a voice disorder.”Connie K. Porcaro, Ph.D., first author and an associate professor in the Department of Communication Sciences and Disorders in FAU’s College of Education Results of the study, published in the Journal of Voice, show that overall, speakers with voice disorders demonstrated a tenfold increase in the number of speech intelligibility errors compared to speakers with healthy voices. In addition to significant differences in the number of errors between healthy speakers and those with voice disorders, listeners also had significantly more overall errors on content words (listener transcribed “cat” for “dog”) than articles (listener transcribed “the” for “a”) with voice type.Related StoriesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTResearch sheds light on sun-induced DNA damage and repairComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchCertain vowels were impacted more than others and noise and lack of harmonic components increased as the severity of perceived voice disorders increased. Seventy-eight percent of the variance associated with intelligibility errors by listeners was due to the presence or absence of voice disorders.The researchers also discovered that the use of listener strategies did not improve speech intelligibility scores and did not increase the number of words correctly transcribed by listeners. Of interest, no matter what strategies listeners were asked to use, the majority of them reported the use of “context” to better understand the speakers and the unintelligible words.Finally, the researchers explored the results of the voice quality ratings and found that speakers with a “breathiness” quality in voice ranging from moderate to severe had a greater number of speech intelligibility errors. Breathiness was the most predictive factor (41 percent) of the variance of speech intelligibility errors. Studies have shown that student auditory comprehension in the classroom is reduced when teachers have voice disorders, which has a negative impact during classroom learning. People with voice disorders may need to take special care to ensure that their listeners understand their intended message and should assess their communicative situations and make appropriate modifications as needed. For example, using gestures or reducing background noise could be useful strategies to improve accuracy and the ability to be understood.”Connie K. Porcaro Source:Florida Atlantic UniversityJournal reference:Porcaro,C.K.et al. (2019) Effect of Dysphonia and Cognitive-Perceptual Listener Strategies on Speech Intelligibility. Journal of Voice. doi.org/10.1016/j.jvoice.2019.03.013
Related StoriesVitamin D metabolite may stop mechanism by which cancer cells become drug-resistantVitamin D and estrogen can prevent heart disease, stroke, and diabetes in womenVitamin D supplement does not prevent type 2 diabetes in adults at high risk, study findsProfessor Gunton says that, compared to a previous study she conducted that looked at mice missing vitamin D receptors across their whole body, this new study has highlighted some important differences.”We found that mice missing muscle cell vitamin D receptors had normal body size but less muscle mass and more fat mass.”In terms of choosing to run on a wheel in their cage, the mice had shorter running distance and slower speed. These might contribute to the lower muscle mass and increase in fat.In terms of muscle strength, these mice also had a significantly decreased grip strength from a very early age.”While more research is needed, Professor Gunton says that these results suggest that maintaining normal vitamin D signaling in muscle is important for preserving muscle bulk and function.”These findings also have the potential to open up avenues to pursue new therapies that target muscle cell vitamin D receptors. These therapies could help to address or prevent age-related sarcopenia (degenerative loss of skeletal muscle mass) and other disorders related to muscle function.” Source:Westmead Institute for Medical Research For a long time, we have known that vitamin D deficiency is associated with muscle weakness and greater risk of falls and fractures. However, whether vitamin D played a direct role in muscle wasn’t known.We show that vitamin D receptor is present in low levels in normal muscle, and our study found that deleting muscle cell vitamin D receptors had important effects on muscle function.” Reviewed by Alina Shrourou, B.Sc. (Editor)Jun 26 2019A recent study conducted at The Westmead Institute for Medical Research has shed light on the role of vitamin D in muscle cells. The study looked at the role of vitamin D in muscles in mice, and showed that vitamin D signaling (how cells communicate with one another) is needed for normal muscle size and strength.Researchers found that mice missing the vitamin D receptor only in myocytes (muscle cells) had smaller muscles, and they were less strong. They also had significantly decreased running speed and didn’t run as far as mice with normal vitamin D action.Lead researcher, Professor Jenny Gunton says:
Drug interactions, including drug-drug interactions (DDIs) and drug-food constituent interactions (DFIs), can trigger unexpected pharmacological effects, including adverse drug events (ADEs), with causal mechanisms often unknown. However, current prediction methods do not provide sufficient details beyond the chance of DDI occurrence, or require detailed drug information often unavailable for DDI prediction. Journal information: Proceedings of the National Academy of Sciences Figure 1. Overall scheme of Deep DDDI and prediction of food constituents that reduce the in vivo concentration of approved drugs. Credit: Korea Advanced Institute of Science and Technology A new method of modeling drug-target interactions fixes a detrimental bias of past techniques Explore further More information: Deep learning improves prediction of drug–drug and drug–food interactions, Proceedings of the National Academy of Sciences (2018). 10.1073/pnas.1803294115 To tackle this problem, Dr. Jae Yong Ryu, Assistant Professor Hyun Uk Kim and Distinguished Professor Sang Yup Lee, all from the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST), developed a computational framework, named DeepDDI, that accurately predicts 86 DDI types for a given drug pair. The research results were published online in Proceedings of the National Academy of Sciences (PNAS) on April 16, 2018, which is titled “Deep learning improves prediction of drug-drug and drug-food interactions.”DeepDDI takes structural information and names of two drugs in pair as inputs, and predicts relevant DDI types for the input drug pair. DeepDDI uses deep neural network to predict 86 DDI types with a mean accuracy of 92.4% using the DrugBank gold standard DDI dataset covering 192,284 DDIs contributed by 191,878 drug pairs. Very importantly, DDI types predicted by DeepDDI are generated in the form of human-readable sentences as outputs, which describe changes in pharmacological effects and/or the risk of ADEs as a result of the interaction between two drugs in pair. For example, DeepDDI output sentences describing potential interactions between oxycodone (opioid pain medication) and atazanavir (antiretroviral medication) were generated as follows: “The metabolism of Oxycodone can be decreased when combined with Atazanavir”; and “The risk or severity of adverse effects can be increased when Oxycodone is combined with Atazanavir”. By doing this, DeepDDI can provide more specific information on drug interactions beyond the occurrence chance of DDIs or ADEs typically reported to date.DeepDDI was first used to predict DDI types of 2,329,561 drug pairs from all possible combinations of 2,159 approved drugs, from which DDI types of 487,632 drug pairs were newly predicted. Also, DeepDDI can be used to suggest which drug or food to avoid during medication in order to minimize the chance of adverse drug events or optimize the drug efficacy. To this end, DeepDDI was used to suggest potential causal mechanisms for the reported ADEs of 9,284 drug pairs, and also predict alternative drug candidates for 62,707 drug pairs having negative health effects to keep only the beneficial effects. Furthermore, DeepDDI was applied to 3,288,157 drug-food constituent pairs (2,159 approved drugs and 1,523 well-characterized food constituents) to predict DFIs. The effects of 256 food constituents on pharmacological effects of interacting drugs and bioactivities of 149 food constituents were also finally predicted. All these prediction results can be useful if an individual is taking medications for a specific (chronic) disease such as hypertension or diabetes mellitus type 2.Distinguished Professor Sang Yup Lee said, “We have developed a platform technology DeepDDI that will allow precision medicine in the era of Fourth Industrial Revolution. DeepDDI can serve to provide important information on drug prescription and dietary suggestions while taking certain drugs to maximize health benefits and ultimately help maintain a healthy life in this aging society.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Deep learning predicts drug-drug and drug-food interactions (2018, April 18) retrieved 18 July 2019 from https://phys.org/news/2018-04-deep-drug-drug-drug-food-interactions.html Provided by The Korea Advanced Institute of Science and Technology (KAIST)
A view of the evacuated houses built under the remains part of the collapsed Morandi highway bridge, in Genoa, northern Italy, Wednesday, Aug. 15, 2018. A bridge on a main highway linking Italy with France collapsed in the Italian port city of Genoa during a sudden, violent storm, sending vehicles plunging 90 meters (nearly 300 feet) into a heap of rubble below. (AP Photo/Nicola Marfisi) Safety codes can lead to over-built bridges, higher building costs This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. But Brencich, who warned two years ago that the design of the bridge was a failure, said the structure should have been destroyed rather than be subjected to more repairs.The Genoa bridge, along with the two similar bridges in Libya and Venezuela, have deteriorated at “unimaginable speeds,” Brencich told Sky News Italian television station Wednesday. “Since this bridge was under constant maintenance, the time had come to consider a replacement for the bridge.”The Italian CNR civil engineering society said structures as old as the Morandi Bridge had surpassed their lifespans. It called for an ambitious plan to repair or replace tens of thousands of Italian bridges and viaducts built in the 1950s and 1960s, citing a series of collapses in recent years, not all fatal.The collapse of a freeway bridge in Minneapolis in 2007 drew similar alarm bells about aging infrastructure in the U.S.The Interstate 35W bridge, whose collapse into the Mississippi river killed 13 people, was also built in the 1960s, though federal investigators ultimately concluded that poor maintenance wasn’t the main cause of the disaster. Instead, they pointed to a design defect, saying crucial gusset plates that held the beams together were only half as thick as they should have been.Since then, there has been a push to improve bridge designs and make changes to the way they are inspected.A more recent fatal collapse involved a newly constructed pedestrian bridge in Florida. U.S. investigators have said they are looking at the emergence of cracks in the structure before the collapse of the bridge near Florida International University, which killed six people.Matteo Pozzi, an associate professor in the Department of Civil and Environmental Engineering at Carnegie Mellon University, said the bridge in Italy “was known to have problems,” as evidenced by the upcoming upgrades. But he said older bridges can often be sustained with maintenance and repairs—and collapses are rare.”It’s still a challenge to predict exactly when, or if, a bridge will collapse,” Pozzi said. “Overall, we are doing a good job because a failure of this kind is rare. But we are trying to improve the ways in which we understand and monitor these bridges.”Of the bridge’s design, Hawkins said the concrete encasement improves the anchorage of the cables but “in a marine environment there can be a buildup of chloride in the concrete and that can lead to cable corrosion.” He said any broken cables would have to be examined to determine whether that was the case in the Morandi bridge.The bridge in Venezuela, which is much larger and spans Lake Maracaibo, also has had mishaps. In 1979, corrosion caused the rupture of one of the concrete-encased cables, forcing a complicated effort to replace it.Pozzi said use of concrete-encased cables for bridges was considered a “pioneering technique” at the time but it was never widely adopted and came to be considered problematic.However, he said there are many bridges around the world whose original technology has been abandoned, and he cautioned against concluding that any are in danger of collapse.More often, it means “there is a maintenance cost,” he said. “The question is for how long and in what way.” Citation: Bridge in Italy had unusual design, required constant work (Update) (2018, August 16) retrieved 18 July 2019 from https://phys.org/news/2018-08-italy-collapse-difficulties-aging-bridges.html The Morandi Bridge was severed in its midsection during a heavy downpour Tuesday. Government officials initially said 39 people were killed but revised the death toll to 38 on Thursday. Italian prosecutors focused their investigation into possible design flaws or inadequate maintenance of the bridge that opened in 1967.Engineering experts said the disaster points to the challenges of maintaining any aging bridge, regardless of its design.”What the general public does not comprehend is that bridges have been traditionally designed in the past for a life span of 50 years,” said Neil Hawkins, a professor emeritus of engineering at the University of Illinois, who specializes in reinforced and prestressed concrete design. “The environment in which the bridge exists can have a major effect on how much it can last beyond that 50-year design life span.”The structure is a cable stayed bridge designed by Italian engineer Riccardo Morandi, who died in 1989. Among its unusual features were its concrete-encased stay cables, which Morandi used in several of his bridge designs instead of the more common steel cables. There are two similar bridges in the world, in Libya and Venezuela.Experts have said a number of factors could have contributed to the collapse, including wear and tear from weather and traffic that surpassed what the bridge was originally built to sustain.”Genoa is a port city so that there can be marine effects and also it is a major industrial center so that there can be air pollution that impairs the concrete,” Hawkins said in an e-mail. “Whether any of these effects, or other major deficiencies in the foundations, were present I have no knowledge. But all can contribute to a bridge failure.”Antonio Brencich, a professor of construction at the University of Genoa, said the design lent itself to swift corrosion and the bridge was in constant need of maintenance.Most recently, a 20 million-euro ($22.7 million) project to upgrade the bridge’s safety had been approved before its collapse, with public bids to be submitted by September. According to the business daily Il Sole 24 Ore, the improvement work involved two weight-bearing columns that support the bridge—including one that collapsed Tuesday. Explore further The bridge that collapsed in the Italian port city of Genoa was considered a feat of engineering innovation when it was built five decades ago, but it came to require constant maintenance over the years. Its design is now being investigated as a possible contributor to its stunning collapse. © 2018 The Associated Press. All rights reserved.
flood Kerala natural disasters Commercial flight operations from the naval airport at Kochi commenced today with the first Air India flight from Bengaluru arriving this morning.Small aircraft are being operated from the naval airport as the Kochi International Airport has shut operations till August 26 following flooding in the heavy rains. The first AI flight from Bengaluru arrived this morning and returned by 0830 hrs.Train services between the state capital and Ernakulam are also gradually returning to normal. Skeletal services run on the Ernakulam-Thiruvananthapuram and Alappuzha-Kottayam routes saw trains packed with flood-affected people moving to the houses of their friends and relatives. The deadly monsoon rains have claimed 210 lives since August 8 and has displaced over 7.14 lakh people from their homes. In the worst affected Chengannur in Alappuzha district, efforts are on to rescue some of those stranded in certain pockets, including Pandanad.According to the India Met Department, a fresh low pressure area had formed over the North West Bay of Bengal yesterday. However, it would not have a significant impact over Kerala, where rainfall is likely to decrease further during the next five days.Rehabilitation will be the next big focus of the state government with most of the marooned having been rescued, Chief Minister Pinarayi Vijayan said.Rainfall over Kerala during the South West Monsoon (June 1 to Aug 19) has been exceptionally high. Kerala has so far received 2,346.6 mm of rain against the normal of 1,649.5 mm, according to IMD.The high-range Idukki district recorded the highest excess rainfall (92 per cent above normal), followed by Palakkad (72 per cent above normal). These two districts have reported several deaths and massive destruction due to flooding and landslides.Thirteen people lost their lives yesterday, while 7,24,649 lakh people were housed in 5,645 relief camps across the state. Rescue operations are in the final stages.Around 22,000 people were rescued yesterday alone in the operations launched by the defence personnel, national and state disaster response forces, fishermen and local people. The next big challenge for the government is containing the spread of epidemic.The Chief Minister said six health officers would be deployed in each panchayat, to ensure there was no outbreak of any communicable diseases as the flood water recedes.People have started returning to their homes from relief centres with flood waters receding. Many were shocked to see the state of their homes, covered with mud and slush as the water receded. Published on August 20, 2018 SHARE SHARE EMAIL airlines and aviation railway SHARE COMMENTS People carry flood relief material to be distributed in flood-affected areas in Thiruvalla in Kerala, on Sunday. – PTI COMMENT
Press Trust of India GopeshwarJuly 12, 2019UPDATED: July 12, 2019 22:41 IST Harish Rawat also accused the BJP government in the state of doing nothing for Gairsain. (Photo: PTI)Former Uttarakhand Chief Minister Harish Rawat Friday courted arrest along with several supporters in Gairsain to protest the recent arrest of 35 demonstrators, demanding a permanent capital status for the hill town in Chamoli district.Harish Rawat was joined by former Assembly speaker Govind Singh Kunjwal, former deputy speaker A P Maikhuri, Congress MLA Karan Mahra and others as he arrived in Gairsain and led a procession to the Ramlila ground there.The former chief minister addressed a public meeting where he accused the BJP government in the state of doing nothing for Gairsain.Rawat said an amount of Rs 45 crore was sanctioned during his chief ministership for the construction of a secretariat in Gairsain but the amount was not utilised by the current dispensation.”Nothing has been done for the hills in the last two years with migration continuing unabated,” he alleged.Rawat led a procession to the tehsil headquarters later and courted arrest along with 115 other party leaders.The demand for the permanent capital status for Gairsain has been raised by different political parties over the years.Also Read | I have played my inning: Congress leader Harish Rawat hints at quitting active politicsAlso Read | Day after Rahul Gandhi, AICC general secretary Harish Rawat resigns citing 2019 poll defeatAlso Watch | Nataka in Karnataka: Rahul Gandhi breaks his silence, says BJP using money power to topple govtsFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byChanchal Chauhan Former Uttarakhand CM Harish Rawat courts arrest in GairsainHarish Rawat was joined by former Assembly speaker Govind Singh Kunjwal, former deputy speaker A P Maikhuri, Congress MLA Karan Mahra and others as he arrived in Gairsain and led a procession to the Ramlila ground.advertisement Next